Sample Pseudo Dating Site

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See table 'Overall remarks' below for full discussion Other kinetic parameters: None. Details on results: The test material was demonstrated to undergo hydrolysis, evident by the formation of orthophosphate, and also by assessment of individual components.

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However, it was not possible to obtain a definitive result for hydrolytic stability since the test material is a complex mixture of phosphates and the concentration of any individual component monitored may be influenced by the hydrolysis of larger complex phosphates. Due to the high volume of tables and figures please see Attachments 4 to 6 Validity criteria fulfilled: yes Conclusions: The test material was demonstrated to undergo hydrolysis, evident by the formation of orthophosphate, and also by assessment of individual components.

Due to volatilisation of the test material during test system preparation, the concentration of the test solutions within each pH gradually decreased, as they were dispensed into their individual test vessels. The actual concentration of the test solutions used for the determination of mass balance was taken from the average of the concentration of the time 0 samples for each pH. Randomisation of the test systems, specifically the Sample Pseudo Dating Site time 0 samples, provided a test solution concentration that was representative of all of the samples within each pH. For test 1 pH 4, 7, and 9, the test solution concentrations were For test 2 pH 4, 7, and 9, the concentrations were

This study is conducted according to an appropriate guideline and under the conditions of GLP and therefore the study is considered to be acceptable and Sample Pseudo Dating Site adequately satisfy both the guideline requirement and the regulatory requirement as a key study for this endpoint. Conclusion The test material was demonstrated to undergo hydrolysis, evident by the formation of orthophosphate, and also by assessment of individual components.

Description of key information The key study for the endpoint 'hydrolysis as a function of pH' Butler RE, has been selected on the basis that the study is conducted to the Sample Pseudo Dating Site OECD guideline and under the conditions of GLP and therefore meets the regulatory requirements for this endpoint.

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The key study reports that the test material is a complex mixture of different types of phosphate and as such no meaningful data could be produced. For this reason, although the test material was observed to be hydrolytically unstable, no further testing Tier 2 was performed.

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It was demonstrated that the more Sample Pseudo Dating Site phosphates indicated by exhibiting longer retention times present in the test material hydrolysed to simpler phosphate species such Sample Pseudo Dating Site orthophosphate, pyrophosphate and tripolyphosphate, all of which were observed to increase significantly during the test. Several components of the test material increased in magnitude during the course of the test.

This is consistent with the process of the phosphate species in the test material hydrolysing to other species already present in solution.

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The amount of orthophosphate present in the test material was initially negligible and not reported as a test material component. During the study the amount of orthophosphate in the sample solutions increased significantly.

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Orthophosphate is therefore considered to Sample Pseudo Dating Site the ultimate hydrolysis product. This theory is supported by the additional supporting literature.

The adsorption properties of the imprinted polymer were demonstrated by equilibrium rebinding experiments, Pseudo-second-order kinetic model, Sips isotherm and Scatchard analysis. The reusability of MIP was checked for at least six repeated batch adsorption cycles and the results showed almost no deterioration in the adsorption capacity. Sample loading and desorption conditions were also optimized.

Key value for chemical safety assessment Additional information Sodium metaphosphate is not considered to be hydrolytically stable, however as the substance, in aqueous solutions, is a complex mixture of phosphate species a half-life was not determined. The ultimate degradation products of sodium metaphosphate are sodium and orthophosphate ions.

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However sodium metaphosphate was also observed to hydrolyse to other phosphate species such as pyrophosphate, trimetaphosphate and tripolyphosphate. All of these species have also been shown to hydrolyse to orthophosphate.

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